Adalat GITS Contraindications

Adalat GITS should not be administered to patients with known hypersensitivity to nifedipine or to other dihydropyridines because of the theoretical risk of cross-reactivity, or to any of the excipients listed in Precautions and Description.
Adalat GITS should not be used in cases of cardiogenic shock, clinically significant aortic stenosis, unstable angina, or during or within one month of a myocardial infarction.
Adalat GITS should not be used for the treatment of acute attacks of angina.
The safety of Adalat GITS in malignant hypertension has not been established.
Adalat GITS should not be used for secondary prevention of myocardial infarction.
Owing to the duration of action of the formulation, Adalat GITS should not be administered to patients with hepatic impairment.
Adalat GITS should not be administered to patients with a history of gastro-intestinal obstruction, oesophageal obstruction, or any degree of decreased lumen diameter of the gastro-intestinal tract.
Adalat GITS must not be used in patients with a Kock pouch (ileostomy after proctocolectomy).
Adalat GITS is contra-indicated in patients with inflammatory bowel disease or Crohn's disease.
Adalat GITS should not be administered concomitantly with rifampicin since effective plasma levels of nifedipine may not be achieved owing to enzyme induction (see Interactions).